Buparvaquone With Furosemide Injection

Each ml contains, Buparvaquone 50 mg furosemide B.P. 55 mgSorbitan mono oleate B.P. 100 mg (as preservative)
Oil base Q.S.

INDICATIONS:

For the treatment of theileriosis (east coast fever) particularly for advanced cases with pulmonary oedema. Buparvaquone kills theilerial schizonts (in lymphoid cells) and piroplasms (in red blood cells) and it suppresses preschizont stages during the Incubation period of the disease.

Buparvaquone kills the parasite through its actions on their mitochondrial electron transport (respiratory) system. Furosemide is a diuretic, which resolves pulmonary oedema.

DOSAGE AND ADMINISTRATION:

Injection by the Intramuscular route into the neck muscles at the rate of 1 ml/20 kg (2.5 mg per kg of buparvaquone and 2.75 mg/kg of furosemide). Repeat after 48 hours. In cases of exceptionally severe infections with pulmonary edema, further treatment at half the dosage rate may be required at 24-hour intervals.

 

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Description

WITHDRAWAL PERIOD

Milk for human consumption should not be taken from animals treated with BUPACIN PLUS until at least 48 hours after treatment. Milk for animals treated with BUPACIN PLUS is safe for consumption by calves. Animals should not be slaughtered for human consumption until at least 42 days after treatment with BUPACIN PLUS.

WARNING / PRECAUTION

Localized swelling may occur at Injection sites but it resolves in a few days. BUPACIN PLUS is very safe so overdosage is unlikely to cause significant adverse effects.

BUPACIN PLUS must be administered only by the Intramuscular route. Intravenous Injection may cause severe shock. BUPACIN PLUS is poorly mobilized after subcutaneous injection and its curative effect is significantly reduced. Furosemide is chemically similar to sulphonamides so BUPACIN PLUS should not be used in animals with sulphonamide sensitivity.

PACK SIZE: 20 ml, 50 ml, 100 ml Vial

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