Each ml contains, Buparvaquone 50 mg furosemide B.P. 55 mgSorbitan mono oleate B.P. 100 mg (as preservative)
Oil base Q.S.

INDICATIONS:

For the treatment of theileriosis (east coast fever) particularly for advanced cases with pulmonary oedema. Buparvaquone kills theilerial schizonts (in lymphoid cells) and piroplasms (in red blood cells) and it suppresses preschizont stages during the Incubation period of the disease.

Buparvaquone kills the parasite through its actions on their mitochondrial electron transport (respiratory) system. Furosemide is a diuretic, which resolves pulmonary oedema.

DOSAGE AND ADMINISTRATION:

Injection by the Intramuscular route into the neck muscles at the rate of 1 ml/20 kg (2.5 mg per kg of buparvaquone and 2.75 mg/kg of furosemide). Repeat after 48 hours. In cases of exceptionally severe infections with pulmonary edema, further treatment at half the dosage rate may be required at 24-hour intervals.