Pen -Strep

Pen-Strep is a mixture of penicillin G and streptomycin that is widely used in mammalian cell culture media to prevent bacterial contamination. The solution contains 200 units of penicillin G which acts as the active base and 200 micrograms of streptomycin.

A combination of Penicillin and Dihydrostreptomycin is indicated in the treatment of conditions such as joint ill, enteritis, and some forms of mastitis caused by bacteria sensitive to Penicillin and/or Streptomycin in cattle, horses, pigs, and sheep.

Dosage & Administration
1ml/25 kg body weight once daily by deep IM injection for up to 3 days.

Max dose at one site:

Cattle 6ml,
Sheep 3ml,
Pigs 1.5ml

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Description

PEN-STREP Injection is indicated for Infections, caused by microorganisms susceptible to penicillin or dihydrostreptomycin, like respiratory-, uterine-, and alimentary tract infections, metritis, mastitis, osteomyelitis, peritonitis, septicemia, cystitis, joint-ill and secondary bacterial infections, in horses, cattle, pigs, foals, calves, sheep, and goats.

Packing:

48 vials of 100 ml in 1 carton.

Composition:

Each ml contains:

Procaine penicillin G.: 200.000 I.U.

Dihydrostreptomycin sulfate: 200 mg.

Indications:

Infections, caused by microorganisms susceptible to penicillin or dihydrostreptomycin, like respiratory-, uterine-, and alimentary tract infections, metritis, mastitis, osteomyelitis, peritonitis, septicemia, cystitis, joint-ill and secondary bacterial infections, in horses, cattle, pigs, foals, calves, sheep and goats.

Contra‑Indications:

Hypersensitivity to penicillins, aminoglycosides and/or procaine, renal dysfunctions, disturbances of auditory or vestibular organ, use in small herbivores like rabbits, chinchillas, and guinea pigs, prolonged use in pregnant animals because of the risk of ototoxicity to the foetus.

Concurrent administration with tetracyclines, chloramphenicol, macrolides, and lincosamides.

Side-effects:

Prolonged administration of high doses may result in renal, vestibular, and/or auditory dysfunctions and sometimes hypersensitivity reactions may occur.

Dosage and Administration: Intramuscular administration.

Cattle: 1 ml per 20 kg bodyweight during 3 consecutive days.

Calves, goats, sheep, and swine: 1 ml per 10 kg bodyweight during 3 consecutive days

Withdrawals

Meat:

  • Cattle 23 days,
  • Sheep 31 days,
  • Pigs 18 days

Milk:

  • Cattle 60 hours.
  • Not for use in sheep producing milk for human consumption

 

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